Abstract

Stevens-Johnson syndrome (SJS) or Toxic epidermal necrolysis (TEN) which were previously called Lyell syndrome is the modified form of same skin conditions. Stevens-Johnson syndrome affects less than 10% of total body surface area and can affect anyone with the genetic predisposition of any gender, age or race. According to recent studies, it is more likely to infect 1 of 1000 people with human immunodeficiency syndrome (HIV). The modern mode of treatment is no doubt had developed a lot but had simultaneously increased adverse side effects and can only suppress the symptoms. Whereas Ayurveda manages disorder naturally and eliminates the root cause. (3) 

What is Stevens-Johnson syndrome?

Stevens-Johnson syndrome (SJS) which was described in 1922 is a rare, cutaneous drug reaction that involves skin and mucous membranes and is characterized by erosions, erythema, blisters, conjunctivitis, purpuric macules, etc. The prevalence of this disease is about 10-30% globally with an incidence of affecting 1-2 individuals per million annually and 1-2 per 1000 with HIV. (1) (2) (3)

Symptoms of Stevens-Johnson syndrome

What are the symptoms of Stevens-Johnson syndrome?

The onset of the disease can have the following clinical features-

  • Fever along with severe body aches and cough
  • Stinging eyes
  • Problem in swallowing
  • Erythema 
  • Eyelid edema
  • Corneal erosion
  • Conjunctival sac
  • Corneal ulceration
  • Hypopigmentation and hyperpigmentation
  • Nail dystrophy
  • Peeling skin
  • Red rashes
  • Blisters on the mucous membrane of mouth, throat, eyes, and genitals
  • Drooling
  • Painful urination
  • Large painful erosions
  • Sealed eyes shut (2)

What causes Stevens-Johnson syndrome?

Some of the factors that trigger the syndrome are as follows-  

Medications

Certain medications like acetaminophen (Tylenol), Aleve, Ibuprofen (Advil, Motrin), Antibiotics (Bactrim and Sulphonamides, etc.), Allopurinol (Zyloprim) and medicines that manage mental illness. Drugs like antiepileptic (Carbamazepine, phenytoin, etc.) and Oxicam, etc. are typically associated with Stevens-Johnson syndrome (SJS). Vaccinations for various diseases like dengue, mycoplasma, and cytomegalovirus can be one of the factors that trigger the initiation of the syndrome. (3)

Infections

Some infections like mycoplasma pneumonia can be the reason for the onset of the disease. It can also affect the person with HIV cancer or weak immune system, mumps, flu, cold sores, Bornholm disease, glandular fever, etc.

Family history

Mutation in the human leukocyte antigen (HLA) gene, drug hypersensitivity or certain genetic factors are closely associated with triggering factors.

How can Stevens-Johnson syndrome be to get diagnosed?

Other than the physical noticeable symptoms some of the clinical tests for diagnosing Stevens-Johnson includes the following details-

  • Blood tests like Complete blood count (CBC) and Liver function tests (LFT)
  • Skin biopsy 
  • Skin cultures to confirm the infection
  • X-ray for pneumonia
  • Patch testing
  • Medical history
  • ECG for cardiac function
  • Tests for renal functions i.e. high uric acid reduced glomerular filtration etc.

What are the complications that may occur?

This disorder if left untreated may lead to other health hazards like sepsis, organ failure, major eye problems and inflammation in various body parts. The liver, kidney, lungs, bone marrow and joints may get affected if the patient is very ill and in pain. Various cardiovascular, gastrointestinal and acute dysfunction in renal systems can occur in the worse cases.

Natural treatment for Stevens-Johnson syndrome

Natural treatment for Stevens-Johnson syndrome by Planet Ayurveda

Ayurvedic medicines are an effective alternative to treat all the disorders naturally without the involvement of any side effect of the medicines. Planet Ayurveda is offering the best treatment for Stevens-Johnson syndrome with the following medicines as discussed below-

Products description

Manjistha capsules

Manjistha capsules have been formulated by pure extracts of Indian traditional herb Manjistha ( Rubia cordifolia ) which is also called Indian madder. This herb is a great blood purifier, detoxifying agent, promotes healing of injury, relieves skin problems, etc. It also possesses anti-bacterial and anti-microbial properties which makes this beneficial in enhancing immunity and improving digestion. This product is very beneficial in maintaining equilibrium in Tridosha i.e. Pitta, Kapha, and Vata.

Dosage- 1-2 capsules two times daily with plain water after meals

2.Immune booster capsules

Immune booster capsules from Planet Ayurveda is a combination of Grapeseed ( Vitis vinifera ), Cow colostrums ( Bovine colostrums ), Bhumi Amla ( Phyllanthus niruri ) and Amalaki ( Phyllanthus emblica ). This herbal blend is packed with essential Vitamins which play a significant role in boosting our immune system. Cow colostrums are a milky fluid rich in vitamins, minerals, carbohydrates, various digestive enzymes, lactoferrin, growth factors, and antibodies. Indian gooseberry or Amalaki works significantly in managing cholesterol levels and reduces symptoms of vitiligo.

Dosage -1-2 capsules two times daily with plain water after meals.

3.Pitta balance capsules

Pitta balance capsule is an amazing herbal remedy containing Coral calcium (Praval pishti), Agate calcium (Akik pishti), Jawar mohra pishti, Kamdudha Ras (Ayurvedic calcium compound), Mukta pishti (Pearl calcium) and Giloy satva ( Tinospora cordifolia ). The combination of the herbs makes it a great blood purifier that helps in maintaining healthy skin. This wonderful product works exceptionally in reducing anger, aggression and negative emotions. The herbs in the formulation make it an excellent remedy for palpitation, skin disorders, acid reflux, ulcers, etc. Overall this product maintains Pitta Dosha and keeps it in a balanced state.

Dosage - 1-2 capsules two times daily with plain water after meals.

4.Gandhak Rasayan tablets

Gandhak Rasayan is a classical Ayurvedic formulation from Planet Ayurveda’s store composed of Purified Sulphur (Shuddh Gandhak). Sulphur is a natural rejuvenating agent making skin lustrous and improves the complexion. It possesses antibacterial, antifungal, antitumor, anti-inflammatory and antidiuretic properties that make it work exceptionally in relieving liver ailments and skin diseases like acne, leprosy, ringworm, scabies and blood impurities. This amazing product is beneficial in relieving burning sensation, treating angioedema, respiratory disorders and being an aphrodisiac agent this efficiently treats sexual dysfunctions.

Dosage -1-2 tablets two or three times daily with lukewarm water.

Why only Planet Ayurveda?

  • All the products are free from additives, colors, preservatives, chemicals, fillers, and binders, etc. 
  • 100 % pure and natural products.
  • 100 % vegetarian products formulated under the strict supervision of MD Ayurveda.
  • Production and manufacturing are done under proper sterilized conditions.
  • Products will not leave you with any side effects.
  • Maintains overall health and immunity.
Author's Bio: 

Dr. Vikram Chauhan (MD Ayurveda) is the CEO and founder of renowned organization Planet Ayurveda and Krishna Herbal Company situated in Mohali (India). He is an expert ayurvedic practitioner with a vision of spreading knowledge about Ancient ayurvedic pharmacy.